Gastroenterology · for healthcare professionals

Established trust.A new chapter.

Two proton pump inhibitors from UROK Pharma for acid-related disorders: ESOROK® 40 mg and the new LansoDex 60 mg.

ESOROK 40 mg carton, 30 capsules LansoDex 60 mg carton, 3 x 10 capsules

Established trust

ESOROK®

Esomeprazole 40 mg capsules

Pack of 30 capsules

Esomeprazole is the S-isomer of omeprazole. It lowers gastric acid by inhibiting the H+/K+-ATPase, the proton pump of the parietal cell.

ESOROK 40 mg carton

Indications and adult dose

Healing of erosive esophagitis

20–40 mg once daily4 to 8 weeks

H. pylori eradicationwith amoxicillin 1000 mg and clarithromycin 500 mg, both twice daily

40 mg once daily10 days

Risk reduction of NSAID-associated gastric ulcer

20–40 mg once dailyup to 6 months

Zollinger-Ellison syndrome and other hypersecretory conditions

40 mg twice dailyadjusted to the patient

How to take

1 hour before a meal

Take at least one hour before eating.

Swallow whole

Do not chew or crush the capsule.

Difficulty swallowing

Open the capsule, mix the granules with a spoon of applesauce and swallow at once. Do not chew the granules.

LansoDex 60 mg carton

A new chapter · new launch

LansoDex

Dexlansoprazole 60 mg modified-release capsules

Pack of 3 × 10 capsules

Dexlansoprazole is the R-enantiomer of lansoprazole. The capsule holds two types of enteric-coated granules that dissolve at different pH levels, so the dose is released in two phases.

Two release phases

0246810 hours after the dose plasma level 1st peak · 1–2 h 2nd peak · 4–5 h
Illustrative curve. The first plasma peak comes 1 to 2 hours after the dose and the second within 4 to 5 hours (dexlansoprazole delayed-release reference data).

Indication and adult dose (60 mg)

Healing of all grades of erosive esophagitis

60 mg once dailyup to 8 weeks

How to take

With or without food

Can be taken at any time relative to meals.

Swallow whole

Do not chew the capsule or the granules.

Difficulty swallowing

Open the capsule, sprinkle the intact granules on a tablespoon of applesauce and swallow at once.

At a glance

ESOROK®LansoDex
Active ingredientEsomeprazoleDexlansoprazole
MoleculeS-isomer of omeprazoleR-enantiomer of lansoprazole
Strength40 mg60 mg
CapsuleCapsuleModified-release capsule
FoodAt least 1 hour before a mealWith or without food
Pack30 capsules3 × 10 capsules

Safety information

Contraindications: known hypersensitivity to the active substance or any excipient; use with rilpivirine-containing products.

Common adverse reactions: diarrhea, abdominal pain and nausea.

Use the lowest dose and the shortest treatment duration suited to the condition. For full prescribing information, see the approved product leaflet.